diff --git a/default.nix b/default.nix
new file mode 100644
index 00000000..934de9d2
--- /dev/null
+++ b/default.nix
@@ -0,0 +1,38 @@
+with (import <nixpkgs> {});
+with python311Packages;
+let
+  glibStorePath = lib.getLib glib;
+in
+stdenv.mkDerivation {
+  name = "piker-poetry-shell-with-qt6";
+  buildInputs = [
+    # System libraries
+    libgcc.lib
+    glib
+
+    # Python requirements.
+    python311Full
+    poetry-core
+  ];
+  src = null;
+  shellHook = ''
+    set -e
+
+    export LD_LIBRARY_PATH=$LD_LIBRARY_PATH:${libgcc.lib}/lib:${glibStorePath}/lib
+
+    # Maybe create venv & install deps
+    poetry install 
+
+    # Use pyqt6 from System, patch activate script
+    ACTIVATE_SCRIPT_PATH="$(poetry env info --path)/bin/activate"
+
+    if grep -q "$PATCH" "$ACTIVATE_SCRIPT_PATH"; then
+        echo "venv is already patched."
+    else
+        echo "patching $ACTIVATE_SCRIPT_PATH"
+        echo "$PATCH" >> "$ACTIVATE_SCRIPT_PATH"
+    fi
+
+    poetry shell
+  '';
+}
diff --git a/develop_headless.nix b/develop_headless.nix
new file mode 100644
index 00000000..934de9d2
--- /dev/null
+++ b/develop_headless.nix
@@ -0,0 +1,38 @@
+with (import <nixpkgs> {});
+with python311Packages;
+let
+  glibStorePath = lib.getLib glib;
+in
+stdenv.mkDerivation {
+  name = "piker-poetry-shell-with-qt6";
+  buildInputs = [
+    # System libraries
+    libgcc.lib
+    glib
+
+    # Python requirements.
+    python311Full
+    poetry-core
+  ];
+  src = null;
+  shellHook = ''
+    set -e
+
+    export LD_LIBRARY_PATH=$LD_LIBRARY_PATH:${libgcc.lib}/lib:${glibStorePath}/lib
+
+    # Maybe create venv & install deps
+    poetry install 
+
+    # Use pyqt6 from System, patch activate script
+    ACTIVATE_SCRIPT_PATH="$(poetry env info --path)/bin/activate"
+
+    if grep -q "$PATCH" "$ACTIVATE_SCRIPT_PATH"; then
+        echo "venv is already patched."
+    else
+        echo "patching $ACTIVATE_SCRIPT_PATH"
+        echo "$PATCH" >> "$ACTIVATE_SCRIPT_PATH"
+    fi
+
+    poetry shell
+  '';
+}